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"description": "Alnylam Pharmaceuticals, Inc. is a biopharmaceutical company primarily dedicated to the discovery, development, and commercialization of innovative therapeutic solutions leveraging ribonucleic acid interference (RNAi) technology. Its robust pipeline of RNAi-based treatments addresses a range of critical therapeutic areas, including inherited genetic disorders, cardio-metabolic conditions, hepatic infectious diseases, and central nervous system (CNS) and ocular disorders. Currently, Alnylam offers several approved therapies: ONPATTRO (patisiran) for adults suffering from polyneuropathy associated with hereditary transthyretin-mediated amyloidosis; GIVLAARI for adult patients with acute hepatic porphyria (AHP); and OXLUMO (lumasiran) for primary hyperoxaluria type 1 (PH1). Beyond its commercial portfolio, the company maintains an active development pipeline. Key investigational therapies include givosiran, aimed at adolescent patients with AHP; patisiran, being explored for transthyretin amyloidosis (ATTR) with cardiomyopathy; cemdisiran for complement-mediated disorders; ALN-AAT02 for AAT deficiency-associated liver disease; ALN-HBV02 for chronic hepatitis B virus infection; Zilebesiran for hypertension; and ALN-HSD for non-alcoholic steatohepatitis (NASH). Additionally, other candidates such as Fitusiran for hemophilia and bleeding disorders, Inclisiran for hypercholesterolemia, an expanded indication for lumasiran for advanced PH1 and recurrent kidney stones, and vutrisiran for ATTR amyloidosis (currently in Phase 3 clinical trials) are also progressing. Alnylam also engages in strategic alliances with other pharmaceutical leaders. Notable collaborations include those with Regeneron Pharmaceuticals, Inc., focused on discovering and developing RNAi therapeutics for ocular and CNS targets, and with Sanofi Genzyme for broader RNAi therapeutic development and commercialization efforts. Further licensing and partnership agreements are in place with entities such as Novartis AG, Vir Biotechnology, Inc., Dicerna Pharmaceuticals, Inc., Ionis Pharmaceuticals, Inc., and PeptiDream, Inc. Established in 2002, Alnylam Pharmaceuticals maintains its corporate headquarters in Cambridge, Massachusetts.",
"ceo": "Yvonne L. Greenstreet",
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"news": [
{
"title": "JP Morgan Maintains Overweight on Alnylam Pharmaceuticals, Lowers Price Target to $400",
"url": "https://www.benzinga.com/news/26/07/60610206/jp-morgan-maintains-overweight-alnylam-pharmaceuticals-lowers-price-target-400",
"source": "benzinga",
"date": "2026-07-22T14:44:08.390000+00:00",
"summary": "JP Morgan analyst Jessica Fye maintains Alnylam Pharmaceuticals (NASDAQ:ALNY) with a Overweight and lowers the price target from $420 to $400."
},
{
"title": "Andra AP fonden Raises Holdings in Alnylam Pharmaceuticals, Inc. $ALNY",
"url": "https://www.defenseworld.net/2026/07/21/andra-ap-fonden-raises-holdings-in-alnylam-pharmaceuticals-inc-alny.html",
"source": "Defense World",
"date": "2026-07-21 03:19:15",
"summary": "Andra AP fonden increased its stake in Alnylam Pharmaceuticals, Inc. (NASDAQ: ALNY) by 78.6% in the undefined quarter, according to the company in its most recent Form 13F filing with the Securities and Exchange Commission. The institutional investor owned 86,697 shares of the bi"
},
{
"title": "Alnylam Pharmaceuticals, Inc. $ALNY Stock Position Lifted by Fifth Third Bancorp",
"url": "https://www.defenseworld.net/2026/07/20/alnylam-pharmaceuticals-inc-alny-stock-position-lifted-by-fifth-third-bancorp.html",
"source": "Defense World",
"date": "2026-07-20 04:30:53",
"summary": "Fifth Third Bancorp grew its position in Alnylam Pharmaceuticals, Inc. (NASDAQ: ALNY) by 7,433.9% in the first quarter, according to its most recent 13F filing with the Securities and Exchange Commission. The fund owned 9,568 shares of the biopharmaceutical company's stock after "
},
{
"title": "Alnylam Pharmaceuticals, Inc. $ALNY Shares Bought by Allspring Global Investments Holdings LLC",
"url": "https://www.defenseworld.net/2026/07/18/alnylam-pharmaceuticals-inc-alny-shares-bought-by-allspring-global-investments-holdings-llc.html",
"source": "Defense World",
"date": "2026-07-18 03:08:15",
"summary": "Allspring Global Investments Holdings LLC grew its stake in Alnylam Pharmaceuticals, Inc. (NASDAQ: ALNY) by 1.1% in the undefined quarter, according to its most recent filing with the SEC. The firm owned 281,793 shares of the biopharmaceutical company's stock after buying an addi"
},
{
"title": "Atlas Healthcare Fund by VST Capital Entered Eli Lilly at $350 in 2020 — The Stock Now Trades Above $1,200",
"url": "https://www.globenewswire.com/news-release/2026/07/17/3329078/0/en/Atlas-Healthcare-Fund-by-VST-Capital-Entered-Eli-Lilly-at-350-in-2020-The-Stock-Now-Trades-Above-1-200.html",
"source": "GlobeNewswire Inc.",
"date": "2026-07-17T12:36:00Z",
"summary": "Atlas Healthcare Fund, managed by VST Capital, showcased its track record of early conviction investments in healthcare, with notable positions in Eli Lilly (entered at $350, now trading above $1,200), Alnylam Pharmaceuticals, TransMedics Group, and Inari Medical. The fund has de"
},
{
"title": "Alnylam to Webcast Conference Call Discussing Second Quarter 2026 Financial Results",
"url": "https://www.businesswire.com/news/home/20260716457592/en/Alnylam-to-Webcast-Conference-Call-Discussing-Second-Quarter-2026-Financial-Results/",
"source": "Business Wire",
"date": "2026-07-16 08:00:00",
"summary": "CAMBRIDGE, Mass.--(BUSINESS WIRE)--Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), the leading RNAi therapeutics company, announced today that it will report financial results for the second quarter ending June 30, 2026 on Thursday, July 30, 2026, before the U.S. financial markets "
},
{
"title": "Alnylam Pharmaceuticals: Commercial Momentum Outweighs TTR Read-Through Concerns",
"url": "https://seekingalpha.com/article/4922526-alnylam-pharmaceuticals-commercial-momentum-outweighs-ttr-read-through-concerns",
"source": "Seeking Alpha",
"date": "2026-07-16 05:44:13",
"summary": "I initiate coverage of Alnylam Pharmaceuticals with a non-consensus BUY rating, citing the recent pullback as an overreaction. AMVUTTRA now holds a near-term commercial monopoly in TTR silencing, with strong clinical data and $890 million in Q1 2026 revenue. ALNY's robust cash po"
},
{
"title": "Oligonucleotide CDMO Market to Reach USD 9.87 Billion by 2031 as RNA-Targeted Drug Pipelines Expand",
"url": "https://www.globenewswire.com/news-release/2026/07/15/3327496/28124/en/Oligonucleotide-CDMO-Market-to-Reach-USD-9-87-Billion-by-2031-as-RNA-Targeted-Drug-Pipelines-Expand.html",
"source": "GlobeNewswire Inc.",
"date": "2026-07-15T08:10:00Z",
"summary": "The global oligonucleotide contract development and manufacturing organization (CDMO) market is experiencing strong growth driven by expanding RNA-targeted medicine pipelines, increased outsourcing of complex synthesis and manufacturing, and rising demand for precision medicine. "
},
{
"title": "Alnylam Highlights Progress with Neuroscience Programs at AAIC 2026, Showcasing Potential of RNAi in Neurological Disease",
"url": "https://www.businesswire.com/news/home/20260715865310/en/Alnylam-Highlights-Progress-with-Neuroscience-Programs-at-AAIC-2026-Showcasing-Potential-of-RNAi-in-Neurological-Disease/",
"source": "Business Wire",
"date": "2026-07-15 03:30:00",
"summary": "CAMBRIDGE, Mass.--(BUSINESS WIRE)--Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), the leading RNAi therapeutics company, today shared advances across its growing neuroscience portfolio at the Alzheimer's Association International Conference (AAIC) 2026. This scientific progress un"
},
{
"title": "Morgan Stanley Raises its Price Target on Alnylam (ALNY)",
"url": "https://finance.yahoo.com/markets/stocks/articles/morgan-stanley-raises-price-target-160956965.html",
"source": "Yahoo! Finance",
"date": "2026-07-14T16:09:56Z",
"summary": "Alnylam Pharmaceuticals, Inc. (NASDAQ:ALNY) is one of the 10 Best Growth Stocks With Highest Upside Potential.\n\nOn July 10, 2026, Morgan Stanley raised the firm's price target on Alnylam Pharmaceuticals, Inc. (NASDAQ:ALNY) to $400 from $370 and kept an Equal Weight rating on the "
},
{
"title": "The Phase 3 Failure That Sent Biotech Winners and Losers in Opposite Directions",
"url": "https://www.marketbeat.com/articles/the-phase-3-failure-that-sent-biotech-winners-and-losers-in-opposite-directions/",
"source": "MarketBeat",
"date": "2026-07-13 12:25:30",
"summary": "When a late-stage clinical trial misses a primary endpoint, the market reaction rarely distributes evenly across the board. The fallout often reveals undeniable fundamental truths about single-asset exposure, pipeline diversification, and the competitive moats protecting establis"
},
{
"title": "Is Alnylam Pharmaceuticals (ALNY) Cheap As Rival Trial Failure Shifts ATTR CM Expectations?",
"url": "https://finance.yahoo.com/markets/stocks/articles/alnylam-pharmaceuticals-alny-cheap-rival-001913229.html",
"source": "Yahoo! Finance",
"date": "2026-07-11T00:19:13Z",
"summary": "Find winning stocks in any market cycle. Join 7 million investors using Simply Wall St's investing ideas for FREE.\n\nAlnylam Pharmaceuticals (ALNY) has drawn fresh attention after shares moved sharply higher, helped by the late stage failure of a competing ATTR cardiomyopathy ther"
},
{
"title": "Ionis Pharmaceuticals Drops Another 9% as Bad News Piles Up",
"url": "https://finance.yahoo.com/healthcare/articles/ionis-pharmaceuticals-drops-another-9-193734273.html",
"source": "Yahoo! Finance",
"date": "2026-07-10T19:37:34Z",
"summary": "* IONS fell 21% this week after the Phase 3 eplontersen ATTR-CM trial missed its primary endpoint, with a monotherapy subgroup hinting at partial efficacy.\n\n* ALNY slipped 3.6% despite analysts flagging its Amvuttra as a direct beneficiary of eplontersen's miss, while BIIB bucked"
},
{
"title": "Is Rival ATTR-CM Trial Failure and New AI Deals Altering The Investment Case For Alnylam (ALNY)?",
"url": "https://finance.yahoo.com/healthcare/articles/rival-attr-cm-trial-failure-191348473.html",
"source": "Yahoo! Finance",
"date": "2026-07-10T19:13:48Z",
"summary": "* In recent days, Alnylam Pharmaceuticals has benefited from the late-stage failure of AstraZeneca and Ionis's competing ATTR-CM trial, alongside expanded AI and regional partnerships that deepen access to its RNAi therapies across new European markets.\n\n* This setback for a key "
},
{
"title": "BBIO Stock Surges 16% As AstraZeneca-Ionis Heart Drug Trial Misses Goal -- BofA Calls Failure 'A Big Surprise'",
"url": "https://finance.yahoo.com/markets/stocks/articles/bbio-stock-surges-16-astrazeneca-190645518.html",
"source": "Yahoo! Finance",
"date": "2026-07-09T19:06:45Z",
"summary": "* Analysts largely viewed the miss as a significant blow to Ionis but not fatal for the company overall.\n\n* BofA Securities called the failure \"a big surprise,\" attributing it to changes in the treatment landscape.\n\n* Raymond James cut its Ionis target to $87 from $104 and remove"
},
{
"title": "Jim Cramer Says Biotech is The Hottest Group in The Market Right Now",
"url": "https://finance.yahoo.com/healthcare/articles/jim-cramer-says-biotech-hottest-153525973.html",
"source": "Yahoo! Finance",
"date": "2026-07-09T15:35:25Z",
"summary": "* Cramer calls IBB the hottest group in the market, up 51% over the past year, with LLY completing four acquisitions in Q1 2026 alone.\n\n* ALNY fell 21% YTD despite 187% revenue growth, the kind of dislocation Cramer says attracts strategic buyers hunting RNAi capabilities.\n\n* A n"
},
{
"title": "US Premarket Movers for July 9, 2026",
"url": "https://www.bloomberg.com/news/articles/2026-07-09/us-stock-futures-today-ionis-levi-salesforce-simply-good-foods",
"source": "Bloomberg Business",
"date": "2026-07-09T11:50:36Z",
"summary": "S&P 500 Index futures climb 0.2% as of 7:43 a.m. in New York. The US military struck Iran for a second day and Tehran retaliated against American allies in the Persian Gulf.\n\n* Nasdaq 100 futures climb 0.7%\n\n* Dow Jones Industrial Average futures are down 0.1%\n\n* The MSCI World I"
},
{
"title": "AstraZeneca Stock and Partner Ionis Sink After Trial Failure. Alnylam Soars.",
"url": "https://www.barrons.com/articles/astrazeneca-stock-ionis-trial-failure-alnylam-40eab20f",
"source": "Barrons",
"date": "2026-07-09 07:38:00",
"summary": "AstraZeneca and California-based biotech Ionis Pharmaceuticals announce a late-stage trial failure for their gene silencing drug, Wainua."
},
{
"title": "Transthyretin Amyloidosis Treatment Market Size to Reach USD 35.10 Billion by 2035, Growing at a 14.64% CAGR | SNS Insider",
"url": "https://www.globenewswire.com/news-release/2026/07/07/3323005/0/en/Transthyretin-Amyloidosis-Treatment-Market-Size-to-Reach-USD-35-10-Billion-by-2035-Growing-at-a-14-64-CAGR-SNS-Insider.html",
"source": "GlobeNewswire Inc.",
"date": "2026-07-07T10:42:00Z",
"summary": "The transthyretin amyloidosis treatment market is projected to grow from USD 8.95 billion in 2025 to USD 35.10 billion by 2035 at a 14.64% CAGR. Growth is driven by increased ATTR-CM diagnosis rates, FDA approvals of gene-silencing therapies like vutrisiran and acoramidis, improv"
},
{
"title": "Can Alnylam's Drug Pipeline Fuel Its Long-Term Revenue Growth?",
"url": "https://www.zacks.com/stock/news/2948673/can-alnylam-s-drug-pipeline-fuel-its-long-term-revenue-growth?cid=CS-STOCKNEWSAPI-FT-analyst_blog|quick_take-2948673",
"source": "Zacks Investment Research",
"date": "2026-07-06 12:56:10",
"summary": "ALNY's advancing pipeline and partnered programs can expand future revenue sources alongside its growing portfolio of approved therapies."
},
{
"title": "What Offers Alnylam Pharmaceuticals (ALNY) Sustained Long-Term Growth?",
"url": "https://finance.yahoo.com/healthcare/articles/offers-alnylam-pharmaceuticals-alny-sustained-115939874.html",
"source": "Yahoo! Finance",
"date": "2026-07-03T11:59:39Z",
"summary": "Brown Advisory, an investment management company, released its \"Brown Large-Cap Growth Strategy\" for the first-quarter 2026 investor letter. A copy of the letter is available to download here. The Brown Advisory Large-Cap Growth Strategy experienced a decline in the first quarter"
},
{
"title": "Wall Street Thinks This Biotech Stock Can Soar 45%. Here's Why Analysts Are Right.",
"url": "https://finance.yahoo.com/healthcare/articles/wall-street-thinks-biotech-stock-105300473.html",
"source": "Yahoo! Finance",
"date": "2026-07-02T10:53:00Z",
"summary": "Shares of Alnylam Pharmaceuticals (NASDAQ: ALNY) have dropped 24% so far this year (through June 30). The biotech company is still a darling of Wall Street analysts, with 14 of 29 analysts following it listing the stock as a buy and seven listing it as a strong buy as I write thi"
},
{
"title": "Komodo Expands Strategic Partnership with Alnylam Pharmaceuticals, Inc. (ALNY)",
"url": "https://finance.yahoo.com/healthcare/articles/komodo-expands-strategic-partnership-alnylam-061706951.html",
"source": "Yahoo! Finance",
"date": "2026-07-02T06:17:06Z",
"summary": "Alnylam Pharmaceuticals, Inc. (NASDAQ:ALNY) is among the Best Fundamental Stocks.\n\nOn June 25, Komodo Health expanded its strategic partnership with Alnylam Pharmaceuticals, Inc. (NASDAQ:ALNY). It is an extension of work built on Komodo's Healthcare Map and Marmot analytics AI pl"
},
{
"title": "Alnylam Pharmaceuticals, Inc. (ALNY) Discusses ALN-6400 RNAi Therapy Targeting Plasminogen for Rare Bleeding Disorders Transcript",
"url": "https://seekingalpha.com/article/4917815-alnylam-pharmaceuticals-inc-alny-discusses-alnminus-6400-rnai-therapy-targeting-plasminogen",
"source": "Seeking Alpha",
"date": "2026-06-25 17:12:09",
"summary": "Alnylam Pharmaceuticals, Inc. (ALNY) Discusses ALN-6400 RNAi Therapy Targeting Plasminogen for Rare Bleeding Disorders Transcript"
},
{
"title": "Komodo Expands Strategic Partnership With Alnylam to Scale AI-Powered Intelligence Platform",
"url": "https://www.businesswire.com/news/home/20260625007024/en/Komodo-Expands-Strategic-Partnership-With-Alnylam-to-Scale-AI-Powered-Intelligence-Platform/",
"source": "Business Wire",
"date": "2026-06-25 09:00:00",
"summary": "NEW YORK & SAN FRANCISCO--(BUSINESS WIRE)-- #AI--Komodo Health®, the leader in AI-powered healthcare intelligence, today announced an expanded strategic partnership with Alnylam Pharmaceuticals (Nasdaq: ALNY), the leading RNAi therapeutics company to scale Marmot™, Komodo's analy"
}
],
"calendar": [
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"revenueActual": null,
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"lastUpdated": "2026-07-23"
},
{
"symbol": "ALNY",
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"epsEstimated": 0.872,
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"revenueEstimated": 1115513000,
"lastUpdated": "2026-07-23"
},
{
"symbol": "ALNY",
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"epsActual": 0.82,
"epsEstimated": 1.16,
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"revenueEstimated": 1149111000,
"lastUpdated": "2026-05-12"
},
{
"symbol": "ALNY",
"date": "2025-10-30",
"epsActual": 2.9,
"epsEstimated": 0.561,
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"revenueEstimated": 959400745,
"lastUpdated": "2026-01-06"
},
{
"symbol": "ALNY",
"date": "2025-07-31",
"epsActual": 0.32,
"epsEstimated": -0.54371,
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"revenueEstimated": 662872241,
"lastUpdated": "2025-10-31"
},
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